Phosgene → 2-(Chlorocarbonyl)-2-[2-(2-methylthioethoxy)-phenyl]-hydrazinecarboxylic acid methyl ester
반응식
[C:1]([Cl:4])(Cl)=[O:2].[CH3:5][O:6][C:7]([NH:9][NH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[O:17][CH2:18][CH2:19][S:20][CH3:21])=[O:8]>C1(C)C=CC=CC=1>[CH3:5][O:6][C:7]([NH:9][N:10]([C:1]([Cl:4])=[O:2])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[O:17][CH2:18][CH2:19][S:20][CH3:21])=[O:8]참가 물질
4
반응 조건
- 온도
- 90 °C
실험 절차
80 ml of a 20% solution of phosgene in toluene are added at 20° C. to 14.1 g of 2-[2-(2-methylthioethoxy)-phenyl]-hydrazinecarboxylic acid methyl ester in 130 ml of toluene. The reaction mixture is subsequently heated for 3 hours at 90° C., and the solvent is then removed. Recrystallisation of the residue in ethyl alcohol yields the compound No. 1.1 of the formula ##STR63## having a melting point of 55°-57° C.