Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Phenylpiperidine → [(1R,2S)-1-Benzyl-2-hydroxy-3-(4-phenyl-piperidin-1-yl)-propyl]-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Phenylpiperidine | HCID 69873 | — |
| 반응물 | erythro-N-Boc-D-phenylalanine epoxide | HCID 11357515 | — |
| 생성물 | [(1R,2S)-1-Benzyl-2-hydroxy-3-(4-phenyl-piperidin-1-yl)-propyl]-carbamic acid tert-butyl ester | HCID 66703612 | — |
반응 단계
Using general procedure 1 and purification method E with [(1R)-1-{(2R)-oxiran-2-yl}-2-phenyl-ethyl]carbamic acid tert-butylester (0.10 g, 0.38 mmol) and 4-phenyl-piperidine (0.122 g, 0.76 mmol) gives the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08106090B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-54ea1127c618433295f4bf6725ef2980 |
| 출처 메모 | uspto-grants-2012_01 |