Sulfamic Acid → 2-Methoxy-5-methylsulfanilic acid
반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:7]([CH3:10])=[CH:8][CH:9]=1)[NH2:6].[S:11](=[O:15])(=[O:14])([OH:13])N>C(#N)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([NH2:6])[C:7]([CH3:10])=[CH:8][C:9]=1[S:11]([OH:15])(=[O:14])=[O:13]참가 물질
4
실험 절차
23.1 g of 3-methoxy-6-methylaniline and 16.4 g of sulfamic acid were put into a 100 ml egg-plant type flask and the mixture was heated to temperature of from 150° to 160° C. and maintained thereat for 2 hours. Acetonitrile was added to the reaction mixture and the crystals thus deposited were collected. The crystals were dissolved in an aqueous solution of sodium hydroxide, the solution was filtered and acidified with hydrochloric acid, and the crystals thus deposited were collected by filtration.
후처리
- temperaturethe mixture was heated to temperature of from 150° to 160° C.
- temperaturemaintained
- customthe crystals thus deposited were collected
- dissolutionThe crystals were dissolved in an aqueous solution of sodium hydroxide
- filtrationthe solution was filtered
- filtrationthe crystals thus deposited were collected by filtration
출처 및 근거
- ORD 기록
- ord-10a5e567c3634c778989865c564fb6c3
- 출처 데이터셋
- uspto-grants-1988_02
- 특허 번호
- US04725531
반응 노트
불러오는 중…