Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromopentane → 7-fluoro-{[5-(trifluoromethyl)-2-furyl]methyl}-1H-indole-2,3-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromopentane | HCID 8057 | — |
| 반응물 | 7-Fluoroisatin | HCID 586418 | — |
| 반응물 | 4-Bromoindole | HCID 676494 | — |
| 반응물 | 2-(Bromomethyl)-5-(trifluoromethyl)furan | HCID 2794605 | — |
| 생성물 | 7-fluoro-{[5-(trifluoromethyl)-2-furyl]methyl}-1H-indole-2,3-dione | HCID 66642570 | — |
반응 단계
Following the procedure as described in PREPARATION 1A, and making tnon-critical variations to replace 4-bromoindole with 7-fluoroisatin, and 1-bromopentane with 2-(bromomethyl)-5-(trifluoromethyl)furan, the title compound was obtained (34%): MS (ES+) m/z 336.2 (M+23).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08106087B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-eeccaab0de1f4b48bffcc4d0c1e23b03 |
| 출처 메모 | uspto-grants-2012_01 |