Benzoic acid, 4-fluoro-, ethyl ester → 2-(2-Chloropyridin-4-yl)-1-(4-fluorophenyl)ethanone

반응식

[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]=1.[F:9][C:10]1[CH:20]=[CH:19][C:13]([C:14](OCC)=[O:15])=[CH:12][CH:11]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([CH2:8][C:14]([C:13]2[CH:19]=[CH:20][C:10]([F:9])=[CH:11][CH:12]=2)=[O:15])[CH:5]=[CH:4][N:3]=1

참가 물질

반응물 2

HCID 67976Benzoic acid, 4-fluoro-, ethyl ester

HCID 772482-Chloro-4-methylpyridine

생성물 1

HCID 108578732-(2-Chloropyridin-4-yl)-1-(4-fluorophenyl)ethanone

실험 절차

Following a similar procedure to that described in reference example 19, but starting from 2-chloro-4-methylpyridine and ethyl 4-fluorobenzoate, the title compound was obtained.

출처 및 근거

ORD 기록: ord-de48c054b3db455a9253c887c96e1425
출처 데이터셋: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08536194B2

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