Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetoacetamide → 1-[6-(4-Fluorophenyl)-2-hydroxy-5-(2-methylsulfanylpyrimidin-4-yl)pyridin-3-yl]ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetoacetamide | HCID 80077 | — |
| 반응물 | 3-Dimethylamino-1-(4-fluorophenyl)-2-(2-methylthiopyrimidin-4-yl)-2-propen-1-one | HCID 67073761 | — |
| 생성물 | 1-[6-(4-Fluorophenyl)-2-hydroxy-5-(2-methylsulfanylpyrimidin-4-yl)pyridin-3-yl]ethanone | HCID 178503414 | — |
반응 단계
Following a similar procedure to that described in reference example 10, but starting from 3-(dimethylamino)-1-(4-fluorophenyl)-2-[2-(methylsulfanyl)pyrimidin-4-yl]prop-2-en-1-one (obtained in reference example 20) and 3-oxobutyramide, the title compound was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536194B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-d3aae47ded0940a59aaa99693a98d066 |
| 출처 메모 | uspto-grants-2013_09 |