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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 425833생성일: 2026년 10월 25일

5-Chloronicotinic acid → (1S,2S,5R)-5-Chloro-N-[7-Methyl-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-nicotinamide

https://huagongshe.com/reaction/425833

반응식

참여 물질

역할이름HCID투입량
반응물5-Chloronicotinic acidHCID 247986—
반응물[(1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]oct-3-yl]-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanoneHCID 59411601—
생성물(1S,2S,5R)-5-Chloro-N-[7-Methyl-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-nicotinamideHCID 25154297—

반응 단계

prepared by reaction of [(1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]oct-3-yl]-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 5-chloro-nicotinic acid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08106215B2
출처 데이터셋uspto-grants-2012_01
ORD IDord-82c65849fddb4b0787acc25e39acd156
출처 메모uspto-grants-2012_01