Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → HCID 66703605, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 2-Fluoro-4-(trifluoromethyl)benzoyl chloride | HCID 145580 | — |
| 반응물 | 7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-one | HCID 33699394 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 66703605 | HCID 66703605 | — |
반응 단계
2-Fluoro-4-(trifluoromethyl)benzoyl chloride was added to a pyridine solution of 7-amino-1-methyl-3,4-dihydroquinolin-2(1H)-one, followed by stirring at room temperature for 12 hours. Water was added to the reaction liquid, followed by stirring for 30 minutes and then the precipitated crystals were collected by filtration to obtain 2-fluoro-N-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-4-(trifluoromethyl)benzamide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08106190B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-37e90418f05547b9ae14e3e6437759f8 |
| 출처 메모 | uspto-grants-2012_01 |