Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- → 4,6-Diphenyl-2-(2-phthalimidoethyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- | HCID 11325 | — |
| 반응물 | 4,6-diphenyl-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine | HCID 67014853 | — |
| 생성물 | 4,6-Diphenyl-2-(2-phthalimidoethyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine | HCID 67014083 | 31% |
반응 단계
Following a similar procedure to that described in examples 6 and 7, but using 4,6-diphenyl-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine (obtained in example 2) instead of 4,6-bis(4-fluorophenyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine and N-(2-bromoethyl)phthalimide instead of iodoethane, the title compound was obtained (yield: 31%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536194B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-04e337fc91c94a5184a2716db9c83c69 |
| 출처 메모 | uspto-grants-2013_09 |