Cyclopropanemethanamine → HCID 68446016, 화합물
반응식
[CH2:1]([O:8][C:9]([NH:11][C:12]1[C:20]2[C:15](=[N:16][C:17]([C:31]3[CH:36]=[CH:35][CH:34]=[C:33]([C:37]([F:40])([F:39])[F:38])[CH:32]=3)=[C:18]([C:21]3[CH:26]=[CH:25][N:24]=[C:23](S(C)(=O)=O)[N:22]=3)[CH:19]=2)[NH:14][N:13]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:41]1([CH2:44][NH2:45])[CH2:43][CH2:42]1>>[CH:41]1([CH2:44][NH:45][C:23]2[N:22]=[C:21]([C:18]3[CH:19]=[C:20]4[C:12]([NH:11][C:9]([O:8][CH2:1][C:2]5[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=5)=[O:10])=[N:13][NH:14][C:15]4=[N:16][C:17]=3[C:31]3[CH:36]=[CH:35][CH:34]=[C:33]([C:37]([F:40])([F:39])[F:38])[CH:32]=3)[CH:26]=[CH:25][N:24]=2)[CH2:43][CH2:42]1참가 물질
3
실험 절차
Following a similar procedure to that described in example 208, but starting from N-benzyloxycarbonyl-[5-(2-methylsulfonylpyrimidin-4-yl)-6-(3-trifluoromethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]amine (obtained in section b) and (cyclopropylmethyl)amine, the desired compound was obtained.
출처 및 근거
- ORD 기록
- ord-00ecfd3894214fb388d83be8eab70ec7
- 출처 데이터셋
- uspto-grants-2013_09