Isonicotinic Acid → Isonicotinoyl chloride hydrochloride

HRID 42628

반응식

HRID 42628 반응식
[C:1]([OH:9])(=O)[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.S(Cl)([Cl:12])=O>>[ClH:12].[C:1]([Cl:12])(=[O:9])[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 5922Isonicotinic AcidHCID 24386Thionyl Chloride

생성물 1

HCID 12262826Isonicotinoyl chloride hydrochloride

실험 절차

A solution of isonicotinic acid (0.10 g, 0.8 mmol) and thionyl chloride (1 mL) were heated to reflux for 2 h and concentrated. The product obtained was used immediately in the following step.

후처리

  1. temperatureto reflux for 2 h
  2. concentrationconcentrated
  3. customThe product obtained

출처 및 근거

ORD 기록
ord-0d0bda2a4ecf4b5fa1825fca2cb4ad7b
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536194B2

연결된 노트

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