HCID 328733, 화합물 → HCID 23455710, 화합물

반응식

[CH:1]1([C:4]([CH:6]=[CH:7][C:8]2[CH:13]=[CH:12][C:11]3[O:14][CH2:15][O:16][C:10]=3[CH:9]=2)=[O:5])[CH2:3][CH2:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:15]1[O:14][C:11]2[CH:12]=[CH:13][C:8]([CH2:7][CH2:6][CH:4]([CH:1]3[CH2:2][CH2:3]3)[OH:5])=[CH:9][C:10]=2[O:16]1

참가 물질

반응물 2

HCID 328733HCID 328733, 화합물

HCID 21226445Aluminium lithium hydride

생성물 1

HCID 23455710HCID 23455710, 화합물

실험 절차

2-(3,4-Methylenedioxyphenyl)ethyl cyclopropyl carbinol [IV; Ar is 3,4-methylenedioxyphenyl, R is H] was prepared from 18.4 g. of 2-(3,4-methylenedioxyphenyl)vinyl cyclopropyl ketone (Preparation A2) and 3.1 g. of lithium aluminum hydride according to the procedure described above in Preparation B1, affording 11.5 g., b.p. 116°-122° C. (0.005 mm.), m.p. 64°-65° C. when recrystallized from ether.

후처리

customaffording 11.5 g
custom, b.p. 116°-122° C. (0.005 mm.), m.p. 64°-65° C. when recrystallized from ether

출처 및 근거

ORD 기록: ord-bdd25be2305c400dad81ee47525c06f9
출처 데이터셋: uspto-grants-1979_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04171378

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