O-Methylhydroxylamine hydrochloride → 6-Ethoxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde O-methyloxime

반응식

[CH2:1]([O:3][C:4]1[N:9]([CH3:10])[C:8](=[O:11])[N:7]([CH3:12])[C:6](=[O:13])[C:5]=1[CH:14]=O)[CH3:2].Cl.[CH3:17][O:18][NH2:19]>>[CH3:17][O:18][N:19]=[CH:14][C:5]1[C:6](=[O:13])[N:7]([CH3:12])[C:8](=[O:11])[N:9]([CH3:10])[C:4]=1[O:3][CH2:1][CH3:2]

참가 물질

반응물 2

HCID 521874O-Methylhydroxylamine hydrochloride

HCID 866586816-Ethoxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde

생성물 1

HCID 866586826-Ethoxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde O-methyloxime

실험 절차

The process described in Method A was followed. 6-Ethoxy-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde (Example 16, Step 1) (0.168 g, 0.79 mmol) and methoxyamine hydrochloride (0.087 g, 1.04 mmol) were used to obtain the title compound.

출처 및 근거

ORD 기록: ord-3d15f98fa702455ea4cc2cb0d2c38eda
출처 데이터셋: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08536210B2

반응 노트

불러오는 중…