참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 3-Amino-4-chloro-2-methylthiomethylbenzotrifluoride | HCID 23352985 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Potassium Hydroxide | HCID 14797 | — |
| 생성물 | Trifluoromethyl toluidine | HCID 2735932 | — |
반응 단계
Dissolve 2 g. of 3-amino-4-chloro-2-methylthiomethylbenzotrifluoride in 50 ml. of 90% ethanol which is 1N in potassium hydroxide. Add 2 teaspoonsful of Raney nickel (W-2). Stir at 70° C. for 3 hours, cool and filter. Add 50 ml. of water and extract three times with hexane. Dry the combined organic extracts and evaporate to yield the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04172095 |
|---|
| 출처 데이터셋 | uspto-grants-1979_10 |
|---|
| ORD ID | ord-392def21d91848d499a8551560e39e13 |
|---|
| 출처 메모 | uspto-grants-1979_10 |
|---|
