2-Norbornene → Methyl 4-(2-aminoanilino)thiophene-3-carboxylate

HRID 427040노트

반응식

HRID 427040 반응식
[NH2:1][C:2]1[CH:17]=[CH:16][CH:15]=[CH:14][C:3]=1[NH:4][C:5]1[CH2:6][S:7][CH2:8][C:9]=1[C:10]([O:12][CH3:13])=[O:11].C12CC(CC1)=CC=2.C12CC(CC1)C=C2>[Pd].C1CCCCC=1>[NH2:1][C:2]1[CH:17]=[CH:16][CH:15]=[CH:14][C:3]=1[NH:4][C:5]1[C:9]([C:10]([O:12][CH3:13])=[O:11])=[CH:8][S:7][CH:6]=1

참가 물질

6

반응물 3

HCID 103522-NorborneneHCID 2819686Methyl 4-(2-aminoanilino)-2,5-dihydrothiophene-3-carboxylateHCID 18006658Norborna-diene

생성물 1

HCID 12658694Methyl 4-(2-aminoanilino)thiophene-3-carboxylate

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8079Cyclohexene용매

실험 절차

Methyl 3-(2-aminoanilino)-2,5-dihydrothiophene-4-carboxylate (2.5 g, 0.001 mol) was added to a flask containing palladium on charcoal catalyst (5%, 200 mg) in cyclohexene (or norbornadiene or norbornylene) (50 ml and the reaction was heated at reflux with stirring for 4 hours, the reaction being followed by t.l.c.

후처리

  1. temperaturethe reaction was heated
  2. temperatureat reflux

출처 및 근거

ORD 기록
ord-bb54b3e1f07d40aea2e53cba5ddc86b6
출처 데이터셋
uspto-grants-1979_10
특허 번호
US04172831

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