Pentanoyl chloride, 4-methyl- → 2-(4-Methyl-1-oxopentyl)furan

HRID 427225노트

반응식

HRID 427225 반응식
C([Sn](CCCC)(CCCC)[C:6]1[O:7][CH:8]=[CH:9][CH:10]=1)CCC.[CH3:19][CH:20]([CH3:26])[CH2:21][CH2:22][C:23](Cl)=[O:24]>C1COCC1.Cl[Pd](Cl)([P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[P](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1>[CH3:19][CH:20]([CH3:26])[CH2:21][CH2:22][C:23]([C:6]1[O:7][CH:8]=[CH:9][CH:10]=1)=[O:24]

참가 물질

5

반응물 2

HCID 170008Pentanoyl chloride, 4-methyl-HCID 43936882-(Tributylstannyl)furan

생성물 1

HCID 952872-(4-Methyl-1-oxopentyl)furan

시약·촉매·용매 2

HCID 178418476HCID 178418476, 화합물촉매HCID 8028Tetrahydrofuran용매

실험 절차

A solution of 2-tributylstannylfuran (1 mmol), 4-methylvaleroyl chloride (1.1 mmol), and PdCl2(PPh3)2 (0.05 mmol) in THF was stirred at 25° C. for 24 h. Extraction and chromatography gave 2-(4-methylvaleryl)furan.

후처리

  1. extractionExtraction and chromatography

출처 및 근거

ORD 기록
ord-4b7281dd45df4ecebc4c09ab97e8a6b1
출처 데이터셋
uspto-grants-2001_11
특허 번호
US06312662B1

반응 노트

불러오는 중…