Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitrogen → 5-(4-Nitro-[1,2,3]triazol-2-ylmethyl)-furan-2-carbaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitrogen | HCID 947 | — |
| 반응물 | (5-((4-nitro-2H-1,2,3-triazol-2-yl)methyl)furan-2-yl)methanol | HCID 67365277 | — |
| 촉매 | Manganese dioxide | HCID 14801 | — |
| 용매 | 2-Oxopropiononitrile | HCID 69430 | — |
| 생성물 | 5-(4-Nitro-[1,2,3]triazol-2-ylmethyl)-furan-2-carbaldehyde | HCID 86649476 | — |
반응 단계
In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), a solution of [5-(4-nitro-[1,2,3]triazol-2-ylmethyl)-furan-2-yl]-methanol (248 mg, 1.11 mmol) in AcCN (11.0 mL) was treated at rt with MnO2 (644 mg, 6.67 mmol). The reaction mixture was stirred at rt overnight before being filtered through Celite and the solvent was removed under reduced pressure. Purification of the residue by FC (40:60 hept-EA) gave the title compound: TLC:rf (40:60 hept-EA)=0.26. LC-MS-conditions 02: tR=0.84 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536209B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-3dcb4a5ff9174205af0466bbdc927706 |
| 출처 메모 | uspto-grants-2013_09 |