Thionyl Chloride → 2-Isopropyl-6-methylbenzylchloride

HRID 427512노트

반응식

HRID 427512 반응식
[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH2:6]O)([CH3:3])[CH3:2].S(Cl)([Cl:15])=O>C(Cl)Cl>[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH2:6][Cl:15])([CH3:3])[CH3:2]

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 18357444(2-Isopropyl-6-methylphenyl)methanol

생성물 1

HCID 183574432-Isopropyl-6-methylbenzylchloride수율 96.3%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a solution of 2-isopropyl-6-methylbenzylalcohol (1.7 g, 10.4 mmol) in methylene chloride (20 ml) was added thionyl chloride (1.7 g, 14 mmol) and the reaction was stirred for 1 h. at room temperature. The solvent was evaporated under reduced pressure and the residue was filrated through silica gel using methylenechloride as eluent. The solvent was evaporated under reduced pressure to give 1.83 g (96%) of the title compound as an oil.

후처리

  1. customThe solvent was evaporated under reduced pressure
  2. customThe solvent was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-3aa176b262cf453884f4ed0481d82783
출처 데이터셋
uspto-grants-2001_11
특허 번호
US06313137B1

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