Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl Peroxide → 1-Bromo-2-(bromomethyl)-3-methylbenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl Peroxide | HCID 7187 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 3-Bromo-o-xylene | HCID 68472 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 1-Bromo-2-(bromomethyl)-3-methylbenzene | HCID 13358318 | 45% |
반응 단계
A mixture of 3-bromo-o-xylene (15 g, 81 mmol), N-bromo succinimid (15.1 g, 85.1 mmol), dibenzoylperoxid (0.65 g) and tetrachloromethane (150 ml) was refluxed for 5 hours. After filtration the filtrate was washed with sodium hydrogensulfite and water. The organic layer was dried over sodium sulfate and evaporated in vacuo. Chromatography (SiO2) (petroleum ether:ethyl acetate, 100:4) gave a 16.8 g fraction of a mixture containing 45% of the title compound. This mixture was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06313137B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-51db4384e25a49baa3d78657a3dfbb95 |
| 출처 메모 | uspto-grants-2001_11 |