Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-amino-N-(4-fluorophenyl)benzamide → 2-[[1-(4-Pyridyl)piperidin-4-ylcarbonyl]amino]-N-(4-fluorophenyl)benzamide Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-amino-N-(4-fluorophenyl)benzamide | HCID 478822 | — |
| 반응물 | 1-(4-Pyridinyl)-4-piperidinecarbonyl chloride | HCID 11183700 | — |
| 생성물 | 2-[[1-(4-Pyridyl)piperidin-4-ylcarbonyl]amino]-N-(4-fluorophenyl)benzamide Hydrochloride | HCID 18174451 | 35% |
반응 단계
Using the procedure described in Example 138, N-(4-fluorophenyl)-2-aminobenzamide (0.92 mmol) and N-(4-pyridyl)isonipecotoyl chloride (1.8 mmol), purifying with RPHPLC Method A, yielded 146 mg (35%) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06313122B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-138d50ea0d944c28934f96cd38175e2d |
| 출처 메모 | uspto-grants-2001_11 |