Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclopentylacetic acid → N-(cyclopentylacetyl)-L-alanine Iso-butyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclopentylacetic acid | HCID 71606 | — |
| 반응물 | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
| 생성물 | N-(cyclopentylacetyl)-L-alanine Iso-butyl Ester | HCID 54023872 | — |
반응 단계
Following General Procedure B above, and using cyclopentylacetic acid (Aldrich) and L-alanine isobutyl ester hydrochloride (from Example B above), the title compound was prepared as a solid having a melting point of 62° C.-64° C. The reaction was monitored by tlc on silica gel (Rf=0.37 in 1:3 EtOAc:hexane) and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06313152B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-390d7096a46f4ae58cc66a46fa8b13ec |
| 출처 메모 | uspto-grants-2001_11 |