2-(3,4-Dihydro-2H-4-chromenylidene)acetonitrile → 2-(Chroman-4-yl)acetonitrile

HRID 428174노트

반응식

HRID 428174 반응식
[O:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[CH:11][C:12]#[N:13])[CH2:3][CH2:2]1>C(O)C.[Pd]>[O:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]([CH2:11][C:12]#[N:13])[CH2:3][CH2:2]1

참가 물질

4

반응물 1

HCID 569848342-(3,4-Dihydro-2H-4-chromenylidene)acetonitrile

생성물 1

HCID 133627812-(Chroman-4-yl)acetonitrile

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

The unsaturated compound obtained in Step A (Z+E mixture), solubilized in ethanol (20 ml), is introduced into the reactor of a Parr apparatus. 10% (by weight) palladium-on-carbon is then added. The double bond is hydrogenated at a pressure of 45 psi for 12 hours.

후처리

  1. additionis introduced into the reactor of a Parr apparatus

출처 및 근거

ORD 기록
ord-b29651a481d64ee3a8572066077af993
출처 데이터셋
uspto-grants-2001_11
특허 번호
US06313160B1

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