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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 428361생성일: 2026년 10월 25일

2-Chloro-6,7-dimethoxy-4-quinazolinamine → Terazosin Hydrochloride Anhydrous

https://huagongshe.com/reaction/428361

반응식

참여 물질

역할이름HCID투입량
반응물2-Chloro-6,7-dimethoxy-4-quinazolinamineHCID 90235—
반응물1-(Tetrahydro-2-furoyl)piperazineHCID 2734641—
생성물Terazosin Hydrochloride AnhydrousHCID 4438373.3%

반응 단계

The procedures of Example 9 were followed except that Compound 3 from Example 1 (3.0 grams, 16.3 mmole) and 4-amino-2-chloro-6,7-bismethoxy quinazoline III (3.8 grams, 16.1 mmole) were reacted to obtain 5.0 grams of Terazosin hydrochloride (Yield: 73%). After alkalification, 4.7 grams of white Terazosin solid was obtained.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06313293B1
출처 데이터셋uspto-grants-2001_11
ORD IDord-d20a34aff01f44b8851f5a208e4967f6
출처 메모uspto-grants-2001_11