Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 4-methylaminobenzoate → Methyl 4-{n-[2-(3-(s)methoxymethoxypyrrolidin-1-yl)-1(r)-phenylethyl]-n-methylamino}benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 4-methylaminobenzoate | HCID 140375 | — |
| 반응물 | 1-Phenylethanol, (R)- | HCID 637516 | — |
| 반응물 | 2-(3-(s)Methoxymethoxypyrrolidin-1-yl)-2-(s)-phenylethanol | HCID 53730535 | — |
| 생성물 | Methyl 4-{n-[2-(3-(s)methoxymethoxypyrrolidin-1-yl)-1(r)-phenylethyl]-n-methylamino}benzoate | HCID 69950347 | 49% |
반응 단계
This was prepared from 2-(3S)-methoxymethoxypyrrolidin-1-yl)-1-(R)-phenylethanol and 2-(3-(S)-methoxymethoxypyrrolidin-1-yl)-2-(S)-phenylethanol and methyl 4-methylaminobenzoate in 49% yield according to a procedure similar to that described in Example 1 (i).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06313302B2 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-698aaac3ba54457094d2ce60cf484a5a |
| 출처 메모 | uspto-grants-2001_11 |