Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 3-(3-Benzyl-3h-imidazol-4-yl)-1-(4-isobutylphenyl)-propen-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4'-Isobutylacetophenone | HCID 93214 | — |
| 반응물 | 1-Benzyl-1H-imidazole-5-carboxaldehyde | HCID 2773239 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-(3-Benzyl-3h-imidazol-4-yl)-1-(4-isobutylphenyl)-propen-1-one | HCID 53707934 | — |
반응 단계
A solution of 4-isobutylacetophenone (2.0 g), 3-benzyl-3H-imidazole-4-carbaldehyde (2.1 g) and 48% sodium hydroxide (0.65 ml) in methanol (20 ml) is heated at 55-60° C. for 6 hours. The reaction mixture is then cooled in an ice bath. The resulting precipitate is filtered, and rinsed with methanol. The yield is 2.5 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06313311B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-9e7a0ec4bf914fee8868b8b03475f04f |
| 출처 메모 | uspto-grants-2001_11 |