DL-Phenylserine → 2-(2-Tert-butoxycarbonyl-ethyl)-5-phenyl-oxazole-4-carboxylic acid

HRID 42879

반응식

HRID 42879 반응식
[CH:1]1[CH:6]=[CH:5][C:4]([CH:7]([OH:13])[CH:8]([NH2:12])[C:9]([OH:11])=[O:10])=[CH:3][CH:2]=1.[C:14]([O:18][C:19](=[O:25])[CH2:20][CH2:21][C:22](O)=O)([CH3:17])([CH3:16])[CH3:15]>>[C:14]([O:18][C:19]([CH2:20][CH2:21][C:22]1[O:13][C:7]([C:4]2[CH:3]=[CH:2][CH:1]=[CH:6][CH:5]=2)=[C:8]([C:9]([OH:11])=[O:10])[N:12]=1)=[O:25])([CH3:17])([CH3:16])[CH3:15]

참가 물질

3

반응물 2

HCID 94134DL-PhenylserineHCID 41391074-(Tert-butoxy)-4-oxobutanoic acid

생성물 1

HCID 669289862-(2-Tert-butoxycarbonyl-ethyl)-5-phenyl-oxazole-4-carboxylic acid

실험 절차

Prepared starting from DL-3-phenylserine hydrate following sequentially general procedures W, X with succinic acid mono-tert-butyl ester, Y and Z. LC-MS-conditions 02: tR=0.95 min; [M+H]+=318.32.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-0379fa74a66648168755aadb24833e17
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536209B2

연결된 노트

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