Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 5-Methyloctahydro-1H-4,7-methanoinden-5-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 4,7-Methano-5H-inden-5-one, octahydro- | HCID 96509 | — |
| 반응물 | HCID 178418332 | HCID 178418332 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 5-Methyloctahydro-1H-4,7-methanoinden-5-ol | HCID 13462505 | — |
반응 단계
Tricyclo [5.2.1.02,6] decan-8-one (15.0 g) in tetrahydrofuran (THF, 50 ml) is slowly added into CH3MgCl (9.7 g) in THF and the reaction mixture is stirred completely. Tetrahydrofuran (THF, 100 ml) with 5% of water is added into the reaction mixture. Then 100 ml of water is added to the reaction mixture. The reaction mixture is extracted by ether. The organic extract is concentrated in vacuo to yield 8-methyl-tricyclo [5.2.1.02,6] decan-8-ol (formula (X)) as white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06316159B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-b35a707df36243debca3a18a173342c1 |
| 출처 메모 | uspto-grants-2001_11 |