rel-(2R,6S)-2,6-Dimethylpiperidine → HCID 70141065, 화합물

HRID 429242

반응식

HRID 429242 반응식
Cl[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([N:20]3[CH2:24][CH2:23][CH2:22][CH2:21]3)=[O:19])=[CH:14][CH:13]=2)=[CH:8][CH:7]=1.[CH3:25][C@@H:26]1[CH2:31][CH2:30][CH2:29][C@H:28]([CH3:32])[NH:27]1>>[CH3:25][C@@H:26]1[CH2:31][CH2:30][CH2:29][C@H:28]([CH3:32])[N:27]1[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([N:20]3[CH2:24][CH2:23][CH2:22][CH2:21]3)=[O:19])=[CH:14][CH:13]=2)=[CH:8][CH:7]=1

참가 물질

3

반응물 2

HCID 641768rel-(2R,6S)-2,6-DimethylpiperidineHCID 22994486[4'-(3-Chloropropoxy)[1,1'-biphenyl]-4-yl](pyrrolidin-1-yl)methanone

생성물 1

HCID 70141065HCID 70141065, 화합물

실험 절차

The product from Example 11A and (2R,6S)-2,6-dimethylpiperidine were processed as described in Example 10F to provide the title compound.

출처 및 근거

ORD 기록
ord-5776e4694b23475da398be011cde973e
출처 데이터셋
uspto-grants-2001_11
특허 번호
US06316475B1

연결된 노트

불러오는 중…