Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Styrene → trans-Stilbene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Styrene | HCID 7501 | — |
| 반응물 | Chlorobenzene | HCID 7964 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 촉매 | Tetraphenylphosphonium Chloride | HCID 164911 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 1,1-Diphenylethylene | HCID 10740 | 14.4% |
| 생성물 | trans-Stilbene | HCID 638088 | 84.9% |
| 생성물 | cis-Stilbene | HCID 5356785 | 0.7% |
반응 단계
A reaction is performed as described in Example 1, except that 10.3 mg (0.04 mmol) of (CH3CN)2PdCl2, 59.7 mg (0.16 mmol) of Ph4PCl, 157.6 mg (1.92 mmol) of anhydrous sodium acetate, 107.1 mg (0.95 mmol) of chlorobenzene and 136.2 mg (1.31 mmol) of styrene in 1 ml of DMF are reacted. Stirring is performed at 150° C. for 8 hours. With 95.6% conversion of Cl-benzene, a 70.4% yield of Heck products (84.9% trans-stilbene, 0.7% cis-stilbene, and 14.4% 1,1-diphenylethene) is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06316675B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-a2489af76f8f455489a19371317c7868 |
| 출처 메모 | uspto-grants-2001_11 |