Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Styrene → trans-Stilbene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Styrene | HCID 7501 | — |
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 촉매 | Tetraphenylphosphonium Chloride | HCID 164911 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 1,1-Diphenylethylene | HCID 10740 | 14.5% |
| 생성물 | trans-Stilbene | HCID 638088 | 85% |
| 생성물 | cis-Stilbene | HCID 5356785 | 0.5% |
반응 단계
A reaction is performed as described in Example 1, except that 3.9 mg (0.015 mmol) of (CH3CN)2PdCl2, 34.9 mg (0.09 mmol) of Ph4PCl, 520.9 mg (6.35 mmol) of anhydrous sodium acetate, 499.6 mg (3.118 mmol) of Br-benzene and 489.3 mg (4.7 mmol) of styrene are reacted in 1.5 ml of DMF. Stirring is performed at 130° C. for 5 hours. According to the processing described in Example 1, a 74.8% yield of Heck products (85.0% trans-stilbene, 0.5% cis-stilbene, and 14.5% 1,1-diphenylethene) is obtained with 74.6% conversion of Br-benzene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06316675B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-1d4146d68dbd45f885d469d03ee4ecc5 |
| 출처 메모 | uspto-grants-2001_11 |