Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → N-(Phenylmethyl)thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | Benzyl Isothiocyanate | HCID 2346 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N-(Phenylmethyl)thiourea | HCID 737375 | 108.1% |
반응 단계
96.3 g (366 mmoles) of benzylisothiocyanate were dissolved in 100 ml o THF and treated with 44.2 ml (732 mmoles) of 32% ammonia solution After 0.5 hour at 40-45° C., 300 ml of water were added and the THF removed in vacuo. The gummy suspension is treated with 200 ml of ether, the crystals collected and washed with water and ether. Suspension in 30 ml of methylenechloride and collection gave 65.77 g (64.2%) of benzyl-2-thiourea with mp 144-5° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06319928B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-ba70aae2e066437bb64b17f50dc28c49 |
| 출처 메모 | uspto-grants-2001_11 |