Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phosgen toluene → HCID 86757603, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phosgen toluene | HCID 19083224 | — |
| 반응물 | HCID 86757605 | HCID 86757605 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | HCID 86757603 | HCID 86757603 | 77.4% |
반응 단계
To a solution of 2 M phosgene/toluene (2.0 ml, 4 mmole) in ethyl ether (20 ml) was added a solution of N-[2-(4-methoxyphenyl-1-methylethyl]-N-ethyl-(piperidin-4-ylmethyl)amine (0.23 grams, 0.79 mmole) in ethyl ether (30 ml). After 30 minutes the precipitate was collected by filtration and dried in vacuo to give N-[2-(4-methoxyphenyl-1-methylethyl]-N-ethyl-(1-chlorocarbonylpiperidin-4-ylmethyl)amine hydrochloride (0.238 grams, 77%), m.p. 144-145° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06319920B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-1ec6e23dc6ff4907bd35a8ee02bb9891 |
| 출처 메모 | uspto-grants-2001_11 |