참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 6-Aminonicotinic acid | HCID 18496 | — |
| 반응물 | 1-Methylpiperazine | HCID 53167 | — |
| 생성물 | (6-Aminopyridin-3-yl)(4-methylpiperazin-1-yl)methanone | HCID 57781845 | — |
반응 단계
The title compound was prepared in analogy to the procedure described in Step 14.1 but using 6-amino-nicotinic acid and 1-methylpiperazine. The reaction mixture was stirred overnight at 0° C. DCM was used for dilution and extraction instead of EtOAc. The dried organic phase was concentrated to afford an impure sample of the title compound which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08536175B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_09 |
|---|
| ORD ID | ord-65aef1e3c6b14e0c923194c276e06732 |
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| 출처 메모 | uspto-grants-2013_09 |
|---|
