4-[2-(Dimethylamino)ethoxy]aniline → 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [4-(2-dimethylamino-ethoxy)-phenyl]-amide

HRID 43084

반응식

HRID 43084 반응식
[CH3:1][N:2]([CH3:13])[CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=1.C(N1CCN(C2C=C(N[C:29]([C:31]3[C:32]4[N:33]=[CH:34][CH:35]=[N:36][C:37]=4[C:38]([C:41]4[C:50]5[C:45](=[CH:46][CH:47]=[CH:48][CH:49]=5)[CH:44]=[N:43][CH:42]=4)=[CH:39][CH:40]=3)=[O:30])C=CC=2)CC1)C>>[CH3:1][N:2]([CH3:13])[CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][C:29]([C:31]2[C:32]3[N:33]=[CH:34][CH:35]=[N:36][C:37]=3[C:38]([C:41]3[C:50]4[C:45](=[CH:46][CH:47]=[CH:48][CH:49]=4)[CH:44]=[N:43][CH:42]=3)=[CH:39][CH:40]=2)=[O:30])=[CH:8][CH:7]=1

참가 물질

3

반응물 2

HCID 64846554-[2-(Dimethylamino)ethoxy]anilineHCID 445156698-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)phenyl]-amide

생성물 1

HCID 445156708-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [4-(2-dimethylamino-ethoxy)-phenyl]-amide

실험 절차

The title compound was prepared in analogy to the procedure described in Step 14.1 but using 4-(2-dimethylamino-ethoxy)-phenylamine (Step 5.1) and 8-isoquinolin-4-yl-quinoxaline-5-car-boxylic acid (Example 52). Title compound: ESI-MS: 464.1 [M+H]+; tR=8.23 min (System 2).

후처리

  1. customThe title compound was prepared in analogy to the procedure

출처 및 근거

ORD 기록
ord-d7be880966c64bc8a4fa752f49260a43
출처 데이터셋
uspto-grants-2013_09
특허 번호
US08536175B2

연결된 노트

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