Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-Methylbenzylamine → 4-(N-benzyl-N-methyl-amino)-dihydro-furan-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-Methylbenzylamine | HCID 7669 | — |
| 반응물 | 2(5H)-Furanone | HCID 10341 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-(N-benzyl-N-methyl-amino)-dihydro-furan-2-one | HCID 69955135 | — |
반응 단계
23.20 ml of N-methylbenzylamine are added to 15.00 g of 5H-furan-2-one in 150 ml methylene chloride. The reaction mixture is stirred for about 48 hours at ambient temperature. For working up the reaction mixture is concentrated by evaporation and chromatographed in batches over a silica gel column with ethyl acetate/petroleum ether (3:1) as eluant. The desired product is obtained as a yellowish oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06656946B2 |
| 출처 데이터셋 | uspto-grants-2003_12 |
| ORD ID | ord-af25213858bc4f09848fe3319cfce942 |
| 출처 메모 | uspto-grants-2003_12 |