Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl 3-oxocyclohexanecarboxylate → HCID 178517489, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl 3-oxocyclohexanecarboxylate | HCID 118096 | — |
| 반응물 | 4-Chlorobenzene-1-carboximidamide hydrochloride | HCID 203436 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | HCID 178517489 | HCID 178517489 | — |
반응 단계
7.5 g of ethyl 2-oxocyclohexane-4-carboxylate and 9.6 g of 4-chlorobenzamidine hydrochloride were introduced into 50 ml of methanol. 5.6 g of potassium tert-butylate were added with stirring. The reaction mixture was stirred under reflux for 4 hours and then poured onto ice water. The crystalline product was filtered off with suction, washed with water and recrystallized from dimethylformamide. Yield: 8.8 g; m.p.: >300° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06660746B1 |
| 출처 데이터셋 | uspto-grants-2003_12 |
| ORD ID | ord-9f7b8dc8f11544988ea9ecdbbc059878 |
| 출처 메모 | uspto-grants-2003_12 |