4-Chloro 2,5-dimethylbenzenesulfonic Acid 2-(isopropyl-(4-chloro 2,5-dimethylbenzenesulfonyl)-amino)-ethyl Ester → 4-Chloro-2,5-dimethyl-N-(2-(4-(5fluoro-1H-benzimidazol-2-yl)-piperidin-1-yl)-ethyl)-N-isopropyl Benzene Sulfonamide
반응식
[CH:1]([N:4]([S:20]([C:23]1[CH:28]=[C:27]([CH3:29])[C:26]([Cl:30])=[CH:25][C:24]=1[CH3:31])(=[O:22])=[O:21])[CH2:5][CH2:6]OS(C1C=C(C)C(Cl)=CC=1C)(=O)=O)([CH3:3])[CH3:2].[F:32][C:33]1[CH:47]=[CH:46][C:36]2[NH:37][C:38]([CH:40]3[CH2:45][CH2:44][NH:43][CH2:42][CH2:41]3)=[N:39][C:35]=2[CH:34]=1>>[Cl:30][C:26]1[C:27]([CH3:29])=[CH:28][C:23]([S:20]([N:4]([CH2:5][CH2:6][N:43]2[CH2:42][CH2:41][CH:40]([C:38]3[NH:37][C:36]4[CH:46]=[CH:47][C:33]([F:32])=[CH:34][C:35]=4[N:39]=3)[CH2:45][CH2:44]2)[CH:1]([CH3:2])[CH3:3])(=[O:21])=[O:22])=[C:24]([CH3:31])[CH:25]=1참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was prepared using the procedure described in Example 1 using D8 and 4-(5-fluoro-1H-benzimidazol-2-yl)piperidine (D17). MH+ 507/509.
출처 및 근거
- ORD 기록
- ord-86979db3c27c4b97bbb8a55680d577b1