2,5 Dibromo-n-(2-chloroethyl)-n-methyl benzene sulfonamide → HCID 178484206, 화합물

반응식

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[S:9]([N:12]([CH2:14][CH2:15]Cl)[CH3:13])(=[O:11])=[O:10].[F:17][C:18]1[CH:32]=[CH:31][C:21]2[NH:22][C:23]([CH:25]3[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]3)=[N:24][C:20]=2[CH:19]=1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][C:3]=1[S:9]([N:12]([CH2:14][CH2:15][N:28]1[CH2:27][CH2:26][CH:25]([C:23]2[NH:22][C:21]3[CH:31]=[CH:32][C:18]([F:17])=[CH:19][C:20]=3[N:24]=2)[CH2:30][CH2:29]1)[CH3:13])(=[O:11])=[O:10]

참가 물질

반응물 2

HCID 187615222,5 Dibromo-n-(2-chloroethyl)-n-methyl benzene sulfonamide

HCID 1785054646-Fluoro-2-(piperidin-4-yl)-1H-benzimidazole

생성물 1

HCID 178484206HCID 178484206, 화합물

실험 절차

The title compound was prepared using the procedure described in Example 1 using 2,5-Dibromo-N-(2-chloroethyl)-N-methyl benzene sulfonamide (D10) and 4-(5-fluoro 1H benzimidazol-2-yl)piperidine (D17). MH+ 5731575/577.

출처 및 근거

ORD 기록: ord-5449e3ef1a6046ab95fcf2542efa594f
출처 데이터셋: uspto-grants-2003_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06660751B1

반응 노트

불러오는 중…