Methyl 4-amino-3-methylbenzoate → 5-Carboxy-2-(3-methyl-n-butyl)indole

반응식

NC1C=CC(C(OC)=O)=CC=1C.[C:13]([C:16]1[CH:17]=[C:18]2[C:22](=[CH:23][CH:24]=1)[NH:21][C:20]([CH2:25][CH2:26][C:27]([CH3:29])=[CH2:28])=[CH:19]2)([OH:15])=[O:14]>>[C:13]([C:16]1[CH:17]=[C:18]2[C:22](=[CH:23][CH:24]=1)[NH:21][C:20]([CH2:25][CH2:26][CH:27]([CH3:29])[CH3:28])=[CH:19]2)([OH:15])=[O:14]

참가 물질

반응물 2

HCID 2736799Methyl 4-amino-3-methylbenzoate

HCID 187616275-Carboxy-2-(2-methyl-1-buten-4-yl)indole

생성물 1

HCID 187616325-Carboxy-2-(3-methyl-n-butyl)indole

실험 절차

Refer to Example 1 using methyl 4-amino-3-methyl-benzoate instead of o-toluidine, or refer to Example 32b) using 5-carboxy-2-(2-methyl-1-buten-4-yl)indole as the starting material.

출처 및 근거

ORD 기록: ord-cac2416b74e54b95998b64fc60afba8f
출처 데이터셋: uspto-grants-2003_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06660763B2

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