Oxalyl chloride → 2-Chloro-5-methylthiobenzoyl chloride
반응식
[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:3]=1[C:4](O)=[S:5].C(Cl)(=O)C([Cl:15])=O>CN(C)C=O>[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:3]=1[C:4]([Cl:15])=[S:5]참가 물질
4
실험 절차
2-Chloro-5-methylthiobenzoic acid (182 mg, 1 mmol) was treated with a solution of oxalyl chloride (1.5 mL of 2 M in dichloromethane, 3 mmol) and a catalytic amount of N,N-dimethylformamide. The reaction was stirred at ambient temperature for 2 hours. The excess oxalyl chloride was removed in vacuo to afford 2-chloro-5-methylthiobenzoyl chloride.
후처리
- customThe excess oxalyl chloride was removed in vacuo
출처 및 근거
- ORD 기록
- ord-6becde9acdaa428b9d53479b1a685665
- 출처 데이터셋
- uspto-grants-2003_12
- 특허 번호
- US06660753B2
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