3-Phenoxybenzoic acid → 3-Phenoxybenzoyl chloride

HRID 431892

반응식

HRID 431892 반응식
[O:1]([C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11](O)=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(Cl)(=O)C([Cl:20])=O>CN(C)C=O>[O:1]([C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11]([Cl:20])=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 195393-Phenoxybenzoic acidHCID 65578Oxalyl chloride

생성물 1

HCID 27603413-Phenoxybenzoyl chloride

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

3-Phenoxybenzoic acid (214 mg, 1.0 mmol) was treated with a solution of oxalyl chloride (1.5 mL of 2 M in dichloromethane, 3 mmol) and a catalytic amount of N,N-dimethylformamide. The reaction was stirred overnight at ambient temperature. The excess oxalyl chloride was removed in vacuo to afford 3-phenoxybenzoyl chloride.

후처리

  1. customThe excess oxalyl chloride was removed in vacuo

출처 및 근거

ORD 기록
ord-e763b04a7795469197e5ffe53186d938
출처 데이터셋
uspto-grants-2003_12
특허 번호
US06660753B2

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