Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Acetylcyclohexene → 2-(1-Cyclohexenyl)-2-butanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Acetylcyclohexene | HCID 13612 | — |
| 반응물 | HCID 178418750 | HCID 178418750 | — |
| 생성물 | 2-(1-Cyclohexenyl)-2-butanol | HCID 10125081 | 56% |
반응 단계
Diethylzinc addition to 1-(1-cyclohexenyl)-ethanone (1.04 mL, 8.05 mmol) was performed according to general procedure A using 2 mol % of Compound B enantiomer (88 mg). The product was purified by column chromatography (hexanes/EtOAc: 96/4) to give 697.1 mg of 9 (56% yield, 96% ee) of a colorless oil: [60 ]D 20=+5.9 (c 3.0, MeOH). [Published [α]D 20=+0.7 (c 3.0, MeOH, 51% ee)].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06660884B2 |
| 출처 데이터셋 | uspto-grants-2003_12 |
| ORD ID | ord-e756d219a0af428290addef8bd61e8fc |
| 출처 메모 | uspto-grants-2003_12 |