Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-bis(3-aminopropyl)methylamine → 1-{3-[4-(3-Aminopropyl)piperazin-1-yl]propyl}amino-7-fluoro-4-nitro-10H-acridin-9-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-bis(3-aminopropyl)methylamine | HCID 7777 | — |
| 반응물 | 1,4-Piperazinediethylamine | HCID 81020 | — |
| 반응물 | 1-{2-[4-(2-aminoethyl)piperazin-1-yl]ethyl}amino-7-fluoro-4-nitro-10H-acridin-9-one | HCID 18760220 | — |
| 반응물 | 1-{3-[methyl(3-aminopropyl)amino]propyl}amino-7-fluoro-4-nitro-10H-acridin-9-one | HCID 18760222 | — |
| 생성물 | 1-{3-[4-(3-Aminopropyl)piperazin-1-yl]propyl}amino-7-fluoro-4-nitro-10H-acridin-9-one | HCID 18760212 | — |
반응 단계
Beginning with N,N-bis(3 -aminopropyl)methylamine, 1-{3-[methyl(3-aminopropyl)amino]propyl}amino-7-fluoro-4-nitro-10H-acridin-9-one (compound 2c) is prepared by the above method. By the same method, but beginning with 1,4-bis(2-aminoethyl)piperazine, it is possible to prepare 1-{2-[4-(2-aminoethyl)piperazin-1-yl]ethyl}amino-7-fluoro-4-nitro-10H-acridin-9-one.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06664263B2 |
| 출처 데이터셋 | uspto-grants-2003_12 |
| ORD ID | ord-c6b2c0ee5770403cb5b7b0800cd572fa |
| 출처 메모 | uspto-grants-2003_12 |