Tris(hydroxymethyl)aminomethane → 1,1-dimethylethyl (2R,6S)-4-{[4-(2-{4-[(4-fluorophenyl)amino]-1-piperidinyl}-1,1-dimethyl-2-oxoethyl)phenyl]methyl}-2,6-dimethyl-1-piperazinecarboxylate

반응식

[CH3:1][C:2]([O:5][C:6]([N:8]1[C@@H:13]([CH3:14])[CH2:12][N:11]([CH2:15][C:16]2[CH:21]=[CH:20][C:19]([C:22]([CH3:27])([CH3:26])[C:23]([OH:25])=O)=[CH:18][CH:17]=2)[CH2:10][C@H:9]1[CH3:28])=[O:7])([CH3:4])[CH3:3].C1CCC(N=C=NC2CCCCC2)CC1.ON1C2C=CC=CC=2N=N1.[F:54][C:55]1[CH:60]=[CH:59][C:58]([NH:61][CH:62]2[CH2:67][CH2:66][NH:65][CH2:64][CH2:63]2)=[CH:57][CH:56]=1.C(O)C(N)(CO)CO.[N-]=C=O>CN(C=O)C.C(Cl)Cl>[F:54][C:55]1[CH:60]=[CH:59][C:58]([NH:61][CH:62]2[CH2:67][CH2:66][N:65]([C:23](=[O:25])[C:22]([C:19]3[CH:18]=[CH:17][C:16]([CH2:15][N:11]4[CH2:12][C@H:13]([CH3:14])[N:8]([C:6]([O:5][C:2]([CH3:3])([CH3:1])[CH3:4])=[O:7])[C@H:9]([CH3:28])[CH2:10]4)=[CH:21][CH:20]=3)([CH3:26])[CH3:27])[CH2:64][CH2:63]2)=[CH:57][CH:56]=1