참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Isooctan-1-ol | HCID 15450 | — |
| 반응물 | Dibutyltin oxide | HCID 61221 | — |
| 반응물 | 2-(3'-tert-Butyl-2'-hydroxy-5'-(2-methoxycarbonylethyl)phenyl)benzotriazole | HCID 93481 | — |
| 생성물 | Octyl 3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propanoate | HCID 9868461 | — |
반응 단계
Methyl 3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyhydrocinnamate (353 g, 1 mol), isooctanol (260 g, 2 mol, from Exxon) and dibutyltin oxide (0.5 g, 0.002 mol) are charged to a reaction flask and heated to 175° C. While heating to 175° C., a 300 mm Hg vacuum is applied. After holding at 175° C. for 30 minutes, the excess isooctanol is distilled by slowly reducing the pressure to <5 mm Hg. The desired product is cooled and discharged. The title compound is obtained in a yield of 451 g (100%) as a light yellow oil whose structure is verified by 1Hnmr and mass spectroscopy. The non-distilled product is analyzed by ICP (Inductively Coupled Plasma) for tin and is found to contain 170 ppm of tin.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06667403B2 |
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| 출처 데이터셋 | uspto-grants-2003_12 |
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| ORD ID | ord-2769a6b740824a9082b1a3a40c5dde14 |
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| 출처 메모 | uspto-grants-2003_12 |
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