Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-Dimethoxyphenethyl alcohol → Methyl 2-Hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-diphenylpropionate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-Dimethoxyphenethyl alcohol | HCID 81911 | — |
| 반응물 | Methyl 3,3-diphenyloxirane-2-carboxylate | HCID 10587027 | — |
| 촉매 | Boron trifluoride etherate | HCID 8000 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Methyl 2-Hydroxy-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-diphenylpropionate | HCID 18756198 | — |
반응 단계
7 g (27.5 mmol) of methyl 3,3-diphenyl-2,3-epoxypropionate and 5.5 g (30.2 mmol) of 2-(3,4-dimethoxyphenyl)ethanol were dissolved in 20 ml of dichloromethane and, at room temperature, 5 drops of boron trifluoride etherate were added. The solution was stirred for 2 hours. The solvent was then distilled off, and the residue (10.7 g, 89%) was immediately reacted further.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06670367B1 |
| 출처 데이터셋 | uspto-grants-2003_12 |
| ORD ID | ord-25a8cc06e044439baf8afa2a89b389b2 |
| 출처 메모 | uspto-grants-2003_12 |