2-Amino-3-pentanone hydrochloride → HCID 178470245, 화합물

반응식

Cl.[NH2:2][CH:3]([C:5](=O)[CH2:6][CH3:7])[CH3:4].F[B-](F)(F)F.[NH:14]=[C:15](SC)[C:16]([O:18][CH2:19][CH3:20])=[O:17]>>[CH2:6]([C:5]1[NH:14][C:15]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[N:2][C:3]=1[CH3:4])[CH3:7]

참가 물질

반응물 2

HCID 193696302-Amino-3-pentanone hydrochloride

HCID 86648451Ethyl imino(methylthio)acetate tetrafluoroborate

생성물 1

HCID 178470245HCID 178470245, 화합물수율 60%

실험 절차

The same operation as in Example (lb) was performed using 2-amino-pentan-3-one hydrochloride obtained in Example (15c) (about 10 mmol) and ethyl imino(methylthio)acetate tetrafluoroborate obtained according to a method known in the literature (J. Med. Chem., 38, 1995, 2196-2201) (about 10 mmol), to obtain 1.1 g of the title compound as a yellow solid (60%).

후처리

customobtained

출처 및 근거

ORD 기록: ord-32f6d9d3694047ab9ccad3ae945efda4
출처 데이터셋: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08536197B2

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