반응식
[CH3:1][C:2]1[NH:6][C:5]([CH:7]=[O:8])=[N:4][C:3]=1[C:9]([F:12])([F:11])[F:10].Cl([O-])=[O:14].[Na+].P([O-])(O)(O)=O.[Na+].CC(=CC)C>>[CH3:1][C:2]1[NH:6][C:5]([C:7]([OH:14])=[O:8])=[N:4][C:3]=1[C:9]([F:12])([F:10])[F:11]참가 물질
5
실험 절차
The same operation as in Example (33c) was performed using 5-methyl-4-(trifluoromethyl)-1H-imidazole-2-carbaldehyde obtained in Example (36c) (90 mg, 0.51 mmol), sodium chlorite (95 mg, 1.05 mmol), sodium dihydrogenphosphate (154 mg, 0.99 mmol) and 2-methyl-2-butene (0.3 mL, 2.84 mmol), to obtain 117 mg of the title compound as a white solid (100%).
출처 및 근거
- ORD 기록
- ord-3d5e398ed2a04ef081f57c6cbf8e141e
- 출처 데이터셋
- uspto-grants-2013_09
- 특허 번호
- US08536197B2
연결된 노트
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