Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-ethyl-3-methylaniline → N-Ethyl-3-Hydroxy-7-Methyl-1,2,3,4-Tetrahydroquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-ethyl-3-methylaniline | HCID 7603 | — |
| 반응물 | Epichlorohydrin | HCID 7835 | — |
| 생성물 | N-Ethyl-3-Hydroxy-7-Methyl-1,2,3,4-Tetrahydroquinoline | HCID 20277626 | — |
반응 단계
N-ethyl-m-toluidine (1.0 mole) and epichlorohydrin (225 g) were mixed and allowed to stand three days at room temperature. The reaction mixture was heated at 140°-145° C. for 6 hrs. and then distilled under vacuum. The product (100 g) which boiled at 143° C. at 1.1 mmHg was recovered in 52% of the theoretical yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04400318 |
| 출처 데이터셋 | uspto-grants-1983_08 |
| ORD ID | ord-6dd8cc6440c04a388d23121a4c921ddc |
| 출처 메모 | uspto-grants-1983_08 |