Benzil-di(beta-bromoethyl)ketal → Benzil-di-(3,3-dimethyl glutarimidoethyl)ketal
반응식
Br[CH2:2][CH2:3][O:4][C:5]([O:20][CH2:21][CH2:22]Br)([C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:13])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[CH3:24][C:25]1([CH3:33])[CH2:31][C:30](=[O:32])[NH:29][C:27](=[O:28])[CH2:26]1.[Na]>>[CH3:24][C:25]1([CH3:33])[CH2:31][C:30](=[O:32])[N:29]([CH2:2][CH2:3][O:4][C:5]([O:20][CH2:21][CH2:22][N:29]2[C:30](=[O:32])[CH2:31][C:25]([CH3:33])([CH3:24])[CH2:26][C:27]2=[O:28])([C:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:13])[C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=2)[C:27](=[O:28])[CH2:26]1참가 물질
3
실험 절차
When 13.26 g of benzil-di-(β-bromoethyl)ketal and 10.63 g of sodium 3,3-dimethylglutarimide were reacted and worked up in the same way as in Example 4, 16.5 g (yield 95.8%) of benzil-di-(3,3-dimethyl glutarimidoethyl)ketal was obtained. Recrystallization from ethanol afforded crystals having a melting point of 130° C.
출처 및 근거
- ORD 기록
- ord-fca13831800340be8dea251590d1485a
- 출처 데이터셋
- uspto-grants-1983_08